Osteoporosis, genetics and hormones

Genetics and Osteoporosis

Osteoporosis is a multifactorial disease influenced by multiple factors and characterized by an imbalance in the regulation of bone remodeling that cause microarchitectural deterioration which compromises the bone strength and leads to bone fragility increasing the fracture risk. Since several years ago, the World Health Organization has considered osteoporosis as one of the most important publ...

2 Genetics and Osteoporosis

Genetics and hormones in testicular descent.

Testicular descent is an essential part of normal male sexual development. Any anomaly that disrupts normal testicular descent will be clinically evident as cryptorchidism. Several factors, such as Hoxa-10, epidermal growth factor (EGF), calcitonin gene-related peptide (CGRP), and hormones, especially androgens and insulin-like factor 3 (INSL-3), have been suggested as being regulators of testi...

Pneumoviruses: Molecular Genetics and Reverse Genetics

Pneumoviruses are responsible for significant respiratory disease in their hosts and represent a major problemfor human and animal health. Pneumoviruses are members of the family Paramyxoviridae, subfamilyPneumovirinae and the virus particles consist of a negative-sense, nonsegmented RNA genome within a helical nucleocapsid structure enveloped in a lipid membrane derived from the ho...

Genetics of osteoporosis--utility of mouse models.